Research
Research and Discovery Successes in 2024-25
The Department of Medicine excels at all stages of the research pipeline from basic discovery, clinical research, and trials, through implementation science and population health. Investments in our investigators and research infrastructure have fueled exponential increases in our department’s research portfolio. Awards for 2024 totaled $154 million.
The department produces about 30% of IU School of Medicine’s total research publications, including about 33% of the high-impact publications produced by the school.
The department’s research goals headed into the next academic year are to continue to increase scientific productivity; increase patient access to clinical trials and clinical research; increase basic science discovery addressing the fundamental mechanisms of health and disease; and increase the impact of departmental research output at system, state, national and global levels.
Largest New Non-Clinical Awards 2024-25
- Kathleen Unroe, General Internal Medicine
NIH/NIA (U24): The NIH Explanatory Trials Network: Supporting Transformation by Enhancing Partnerships (The NEXT STEPS)
$3,130,685 - Adrian Gardner, Infectious Diseases & Center for Global Health
Eli Lilly & Company: AMPATH/MAPAS Mexico: Building Community Capacity & Strengthening Health Systems for Non-Communicable Diseases (NCDs) in Puebla, Mexico
$3,059,283 - Adrian Gardner, Infectious Diseases & Center for Global Health
Lilly Foundation: AMPATH Global NCD Initiative: Kenya, Ghana and Nepal
$2,500,000 - Tim Richardson, Clinical Pharmacology
NIH/NIA (U01): Optimization of SHIP1 Inhibitors for the Treatment of Alzheimer’s Disease
$2,217,438 - Adrian Gardner, Infectious Diseases & Center for Global Health
M & S Dell Foundation: Providing Life-Changing Cardiac Surgeries in Kenya
$1,000,001 - Tim Richardson, Clinical Pharmacology
NIH/NIA (R01): siRNA-mediated Knockdown of INPP5D to Modulate Microglia Activity for the Treatment of Alzheimer’s Disease
$792,074 - Laura Ruhl, General Internal Medicine & Center for Global Health
Abbvie Foundation: Abbvie 2024-2025 To Strengthen Health Systems in Kenyan Counties and Provide Equitable Care Addressing Social & Economic Determinants that Lead to Poor Health Outcomes
$770,000 - Homer Twigg, Pulmonary & Critical Care
NIH/NHLBI (R01): Analysis of Immunologic Mechanisms in Patients with Chronic Lung Disease After Acute COVID Infection
$752,410